The advertisement states: "A most significant event was the discovery of bacteria in 1675 by Antoni van Leeuwehhoek who used a primitive microscope of his own manufacture." Thus, the connection to Bausch & Lomb Optical of Rochester, New York!

van Leeuwenhoek is best known for his work on the improvement of the microscope and for his contributions towards the establishment of microbiology. Using his handcrafted microscopes, he was the first to observe and describe single-celled organisms, which he originally referred to as animalcules, and which we today refer to as microorganisms. He was also the first to record microscopic observations of muscle fibers, bacteria, spermatozoa and blood flow in capillaries. During his lifetime, van Leeuwenhoek ground over 500 optical lenses, and created over 400 different types of microscopes.

This 1950's advertisement is framed in a vintage, circa 1910, beautifully grain-painted, plaster-on-wood frame measuring 18 inches wide x 23 1/2 inches long. The frame has numerous small chips and abrasions but remains sturdy and is handsome despite its difficulties. The piece is backed with cardboard.

The print itself was subject to water at one point and has evidence of water marks on the bottom as seen in the photos. There is a superficial, inverted "V" shaped scratch in the center (again, see photos) and a rub to the left of the female's head (see photos).